Two people from Auburn were injured late Sunday after the vehicle they were riding in rolled on state Route 18, the State Patrol reported.
The accident happened about 11:40 p.m. in the eastbound lanes of SR 18 at Peasley Canyon.
Troopers said its unclear what caused the 42-year-old driver to lose control of the 2009 Chevrolet Aveo, which hit a guardrail and rolled over.
The freeway was blocked for two hours while the State Patrol investigated the collision.
Both the driver and his 44-year-old passenger were taken to Harborview Medical Center in Seattle with unknown injuries.